The use of the Cas9 enzyme that allows DNA editing is becoming increasingly controversial. | Image: shutterstock/Juan Gaertner

News: Regulation for gene editing

The world was shocked in November 2018 to learn of the birth in China of the first babies whose heritable DNA had been genetically modified. The principal investigator was subsequently fired and faces an investigation. A number of prominent biologists have now called for “a global moratorium on all clinical uses of human germline editing”, a clearer demand than the statement made during the International Summit on Human Gene Editing in 2015, which considered that “each nation ultimately has the authority to regulate”. A new committee of the World Health Organization would prefer to exert control: it urges the creation of an international registry for all experiments related to human genome editing.

News: How to open up your research

Researchers should “integrate Data Management Plans with the workflows of all stakeholders in the research data ecosystem”. This is the first of ten principles for managing open research data put forward by Tomasz Miksa in PLOS, which aim to make data accessible to algorithms. But openness should be viewed “as a continuum”, writes Pablo Diaz from the Swiss Centre of Expertise in the Social Sciences (FORS), who urges us to consider ethical considerations in a recently published guide.

In numbers: 42%

The Brazilian government has frozen nearly half the annual budget of its Ministry of Science.

In numbers: 33%

A third of research universities explicitly support the use of the Journal Impact Factor (a proxy for a scientific journal’s reputation) in assessing career promotions, according to a survey of 57 institutions in North America.

Quotes
“We must abandon the assumption that a passive apprentice system works”.
Australia’s Chief Scientist Alan Finkel writes in Nature that we need explicit instructions for research integrity and professional expectations.
“In some labs, it’s a toxic culture of overwork”
says the PhD student Katerina Gonzales, writing in the Stanford Daily.
“Software cannot determine plagiarism; it can only point to some cases of matching text”.
Debora Weber-Wulff, digital media specialist at HTW Berlin, condemns our overreliance on technology in Nature.